SCHEMBL6509907

SCHEMBL6509907

O=C(O)c1cc(-c2cc(C(=O)O)nc(C(=O)O)c2)cc(C(=O)O)n1

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.67
TSHR P16473 2/20 0.67
HIF1A Q16665 1/20 0.67
TDP1 Q9NUW8 2/20 0.55
KDM4E B2RXH2 1/20 0.55
ACMSD Q8TDX5 1/20 0.55
MCL1 Q07820 11/20 0.53
LMNA P02545 1/20 0.43
KMO O15229 2/20 0.41
GPR35 Q9HC97 1/20 0.41
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1759786 0.88 MCL1 (0.64) ALOX15TSHRHIF1ATDP1KDM4E
SCHEMBL17595151 0.84 MCL1 (0.56) ALOX15TSHRHIF1ATDP1KDM4E
SCHEMBL21044531 0.84 MCL1 (0.51) ALOX15TSHRHIF1ATDP1KDM4E
SCHEMBL31401885 0.84 TSHR (0.61) ALOX15TSHRHIF1AMCL1
SCHEMBL17595055 0.82 MCL1 (0.54) ALOX15TSHRHIF1AKDM4EMCL1
SCHEMBL17594949 0.82 SCN9A (0.56) ALOX15TSHRHIF1ATDP1KDM4E
SCHEMBL21044577 0.82 MCL1 (0.69) ALOX15TSHRHIF1AMCL1KMO
SCHEMBL4772052 0.81 ALOX15 (0.46) ALOX15TSHRHIF1ATDP1KDM4E
SCHEMBL19182234 0.81 RXRA (0.58) ALOX15TSHRHIF1AMCL1KMO
SCHEMBL336311 0.80 TSHR (1.00) ALOX15TSHRHIF1ATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4397399-A2 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2024-07-10 EP claimed
CN-114990533-A Method for improving copper electroplating binding force of ceramic substrate surface 江苏富乐华半导体科技股份有限公司 2022-09-02 CN claimed
CN-109503474-B Synthesis method of 2,2',6,6' -tetracarboxyl- [4, 4' -bipyridine ] 湖南科技大学 2021-10-08 CN claimed
US-12629639-B2 Spacer for a spiral wound membrane EVOVE LTD (GB) 2026-05-19 US disclosed
EP-4397399-A2 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2024-07-10 EP disclosed
US-20240157304-A1 SPACER FOR A SPIRAL WOUND MEMBRANE EVOVE LTD (GB) 2024-05-16 US disclosed
US-20240149223-A1 MEMBRANE DEVICE EVOVE LTD (GB) 2024-05-09 US disclosed
EP-4304766-A1 MEMBRANE DEVICE Evove Ltd (GB) 2024-01-17 EP disclosed
EP-4304765-A1 SPACER FOR A SPIRAL WOUND MEMBRANE Evove Ltd (GB) 2024-01-17 EP disclosed
WO-2022189793-A1 MEMBRANE DEVICE EVOVE LTD (GB) 2022-09-15 WO disclosed
WO-2022189785-A1 SPACER FOR A SPIRAL WOUND MEMBRANE EVOVE LTD (GB) 2022-09-15 WO disclosed
CN-114990533-A Method for improving copper electroplating binding force of ceramic substrate surface 江苏富乐华半导体科技股份有限公司 2022-09-02 CN disclosed
CN-109503474-B Synthesis method of 2,2',6,6' -tetracarboxyl- [4, 4' -bipyridine ] 湖南科技大学 2021-10-08 CN disclosed
CN-109503474-B Synthesis method of 2,2',6,6' -tetracarboxyl- [4, 4' -bipyridine ] 湖南科技大学 2021-10-08 CN disclosed
CN-109503474-B Synthesis method of 2,2',6,6' -tetracarboxyl- [4, 4' -bipyridine ] 湖南科技大学 2021-10-08 CN disclosed
US-8824048-B2 Anisotropic dye layer, coordination polymer for anisotropic dye layer and polarization element, and polarization control film, polarization control element, multi-layer polarization control element, ellipse polarization plate, light emission element, and method for controlling polarization properties employing the anisotropic dye layer KONICA MINOLTA OPTO, INC. (JP) 2014-09-02 US disclosed
US-20130235552-A1 ANISOTROPIC DYE LAYER, COORDINATION POLYMER FOR ANISOTROPIC DYE LAYER AND POLARIZATION ELEMENT, AND POLARIZATION CONTROL FILM, POLARIZATION CONTROL ELEMENT, MULTI-LAYER POLARIZATION CONTROL ELEMENT, ELLIPSE POLARIZATION PLATE, LIGHT EMISSION ELEMENT, AND METHOD FOR CONTROLLING POLARIZATION PROPERTIES EMPLOYING THE ANISOTROPIC DYE LAYER KONICA MINOLTA OPTO, INC. (JP) 2013-09-12 US disclosed
US-8472115-B2 Anistropic dye layer, coordination polymer for anistropic dye layer and polarization element, and polarization control film, polarization control element, multi-layer polarization control element, ellipse polarization plate, light emission element, and method for controlling polarization properties employing the anistropic dye layer KONICA MINOLTA OPTO, INC. (JP) 2013-06-25 US disclosed
US-6893716-B2 Non-covalent assembly of multilayer thin film supramolecular structures WORCESTER POLYTECHNIC INSTITUTE (US) 2005-05-17 US disclosed
US-20040110009-A1 Non-covalent assembly of multilayer thin film supramolecular structures WORCESTER POLYTECHNIC INSTITUTE 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629639-B2 Spacer for a spiral wound membrane AQP1, AQP3, AQP4 ALOX15 4184/4885TSHR 394/4885HIF1A 848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.