Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 4/20 | 0.43 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.39 |
| ▸ | STAT5A | P42229 | 2/20 | 0.39 |
| ▸ | STAT5B | P51692 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 2/20 | 0.38 |
| ▸ | PYGM | P11217 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12552719 | 0.86 | DRD2 (0.41) | STAT6CYP51A1DRD2PYGLPYGM | |
| SCHEMBL1931296 | 0.86 | DRD2 (0.41) | STAT6CYP51A1DRD2PYGLPYGM | |
| SCHEMBL1931082 | 0.86 | DRD2 (0.41) | STAT6CYP51A1DRD2PYGLPYGM | |
| SCHEMBL14980442 | 0.85 | STAT6 (0.48) | STAT6CYP51A1DRD2CCKBR | |
| SCHEMBL7934440 | 0.85 | STAT6 (0.48) | STAT6CYP51A1DRD2CCKBR | |
| SCHEMBL7943270 | 0.84 | STAT6 (0.48) | STAT6CYP51A1DRD2CCKBRELANE | |
| SCHEMBL7934126 | 0.83 | STAT6 (0.48) | STAT6CYP51A1DRD2CCKBR | |
| SCHEMBL16474116 | 0.81 | STAT6 (0.45) | STAT6CYP51A1STAT5ADRD2KDM5A | |
| SCHEMBL7945427 | 0.81 | STAT6 (0.45) | STAT6CYP51A1DRD2KDM5ACCKBR | |
| SCHEMBL7941160 | 0.81 | STAT6 (0.45) | STAT6CYP51A1DRD2PYGLCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011914-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |