Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL817237 | 0.77 | — | — | |
| SCHEMBL8155067 | 0.77 | ACHE (0.38) | LMNATSHRALOX12ACHE | |
| SCHEMBL2972001 | 0.77 | — | — | |
| SCHEMBL28815088 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL28815092 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL217868 | 0.75 | EED (0.36) | ACHE | |
| SCHEMBL7931699 | 0.75 | CYP2A6 (0.43) | LMNATSHR | |
| SCHEMBL6648005 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL218457 | 0.75 | NPC1 (0.38) | TSHRACHE | |
| SCHEMBL6650647 | 0.75 | ACHE (0.38) | LMNATSHRALOX12ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300376-B1 | FOR THERAPY TO ACHIEVE SMOOTH MUSCLE RELAXING ACTIVITY AND/OR MAST CELL STABILIZING ACTIVITY AND/OR ANTI-INFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IR) | 2001-10-09 | — | — | US | claimed |
| EP-2734497-A1 | INDANE DIMERS FOR USE IN THE TREATMENT OF AUTOIMMUNE INFLAMMATORY DISEASE | Venantius Limited (IE) | 2014-05-28 | — | — | EP | disclosed |
| WO-2013014660-A1 | INDANE DIMERS FOR USE IN THE TREATMENT OF AUTOIMMUNE INFLAMMATORY DISEASE | VENANTIUS LIMITED (IE) | 2013-01-31 | — | — | WO | disclosed |