Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941650 | 0.86 | ADAM17 (0.66) | ADAM17TNF | |
| SCHEMBL10263513 | 0.81 | ADAM17 (0.58) | ADAM17TNF | |
| SCHEMBL10263357 | 0.74 | ADAM17 (0.69) | ADAM17TNF | |
| SCHEMBL10263515 | 0.73 | ADAM17 (0.74) | ADAM17TNF | |
| SCHEMBL7935221 | 0.73 | TNF (0.49) | ADAM17TNF | |
| SCHEMBL7941661 | 0.72 | ADAM17 (0.72) | ADAM17TNF | |
| SCHEMBL7944486 | 0.72 | ADAM17 (0.58) | ADAM17TNF | |
| SCHEMBL7945166 | 0.71 | ADAM17 (0.74) | ADAM17TNF | |
| SCHEMBL7941689 | 0.70 | ADAM17 (0.67) | ADAM17TNF | |
| SCHEMBL7944317 | 0.70 | ADAM17 (0.73) | ADAM17TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054278-A2 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |