⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15867247 | 0.83 | — | — | |
| SCHEMBL15075716 | 0.83 | — | — | |
| SCHEMBL14384791 | 0.81 | — | — | |
| SCHEMBL9647050 | 0.77 | — | — | |
| SCHEMBL14217535 | 0.77 | — | — | |
| SCHEMBL7540308 | 0.72 | — | — | |
| SCHEMBL15355136 | 0.71 | ALDH1A1 (0.30) | — | |
| SCHEMBL18944438 | 0.70 | — | — | |
| SCHEMBL1683755 | 0.69 | — | — | |
| SCHEMBL24302264 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-116710425-A | Pharmaceutical agents for the treatment of disorders involving lannodine receptors | 阿姆果制药有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117440954-A | Metabolic stable pyrimidinyl dihydroquinoxalinones as tubulin polymerization inhibitors | 田纳西大学研究基金会 | 2024-01-23 | — | — | CN | disclosed |
| CN-116710425-A | Pharmaceutical agents for the treatment of disorders involving lannodine receptors | 阿姆果制药有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-114269383-A | Metalloenzyme inhibitor compounds | 菲斯生物制药公司 | 2022-04-01 | — | — | CN | disclosed |
| EP-3892618-A1 | 4-PYRIDINYL FORMAMIDE COMPOUND OR DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |
| WO-2021126080-A1 | A NEW METHOD OF 18F LABELLING AND INTERMEDIATE SALTS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2021-06-24 | — | — | WO | disclosed |
| WO-2018098500-A1 | COMPOUNDS AND THEIR METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2018-05-31 | — | — | WO | disclosed |
| EP-2218716-B1 | METHOD FOR AMPLIFYING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND | NISSAN CHEMICAL IND LTD (JP) | 2016-11-16 | — | — | EP | disclosed |
| WO-2010015652-A2 | THIAZOLE COMPOUNDS AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-11 | — | — | WO | disclosed |
| EP-1663983-B1 | N-SUBSTITUTED, 6,8-DIALKOXY-1,2,3,4-TETRAHYDRO-1H-ISOQUINOLINE AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2009-01-21 | — | — | EP | disclosed |
| WO-2008141077-A1 | PROCESS FOR THE PREPARATION OF TETRAHYDROQUINOLINYL, BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008079427-A1 | 1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-07-03 | — | — | WO | disclosed |
| WO-2007134149-A2 | 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE AND THIAZINE DERIVATIVES AS CETP INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-22 | — | — | WO | disclosed |