SCHEMBL7944012

SCHEMBL7944012

COC(=O)[Si](C(=O)OC)(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
SRC P12931 1/20 0.44
CES1 P23141 5/20 0.42
CES2 O00748 3/20 0.42
KMT2A Q03164 2/20 0.42
ALOX15 P16050 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
F2 P00734 1/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
NPC1 O15118 5/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15053482 0.75 ALDH1A1 (0.44) TSHRKMT2AALOX15SMN1; SMN2KDM4E
SCHEMBL28420886 0.74 TSHR (0.52) TSHRSRCCES1CES2KMT2A
Methyl Benzoate SCHEMBL27601056 0.73 TSHR (0.95) TSHRKMT2ASMN1; SMN2MEN1MAPT
Methyl Benzoate SCHEMBL28232728 0.71 TSHR (0.91) TSHRKMT2ASMN1; SMN2MEN1MAPT
Methyl Benzoate SCHEMBL28945661 0.70 TSHR (1.00) TSHRKMT2ASMN1; SMN2MEN1MAPT
Methyl Benzoate SCHEMBL1332323 0.70 TSHR (1.00) TSHRKMT2ASMN1; SMN2MEN1MAPT
Methyl Benzoate SCHEMBL29831725 0.70 TSHR (1.00) TSHRKMT2ASMN1; SMN2MEN1MAPT
SCHEMBL14760260 0.70 CES2 (0.57) TSHRCES1CES2KMT2ASMN1; SMN2
Methyl Benzoate SCHEMBL1867855 0.70 TSHR (1.00) TSHRKMT2ASMN1; SMN2MEN1MAPT
Methyl Benzoate SCHEMBL7200 0.70 TSHR (1.00) TSHRKMT2ASMN1; SMN2MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0709415-B1 Substrat coated by a base-coat and a clear coat, method of film-forming and coated articles NOF CORP (JP) 2001-07-25 EP disclosed
US-6030571-A Methods of molding and molded articles made thereby NOF CORPORATION (JP) 2000-02-29 US disclosed
US-5922633-A THERMAL LATENT ACID CATALYST CONSISTS OF AN EPOXY COMPOUND, A SULFUR COMPOUND AND LEWIS ACID NOF CORPORATION (JP) 1999-07-13 US disclosed
US-5661219-A AN ACRYLIC COPOLYMER HAVING CARBOXY GROUPS BLOCKED BY A VINYL ETHER, A REACTIVE POLYMER, E.G.HAVING EPOXY GROUPS, AND LEWIS ACID-COMPLEX CATALYST; HIGH SOLIDS; LOW TEMPERATURE CURING; STORAGE STABILITY; MECHANICAL PROPERTIES NOF CORPORATION (JP) 1997-08-26 US disclosed
EP-0643112-B1 Curable composition, thermal latent acid catalyst, method of coating, coated article, method of molding and molded article NOF CORP (JP) 1997-07-30 EP disclosed
EP-0709415-A2 Curable base-coat composition, method of film-forming and coated articles NOF CORPORATION (JP) 1996-05-01 EP disclosed
EP-0643112-A2 Curable composition, thermal latent acid catalyst, method of coating, coated article, method of molding and molded article NOF CORPORATION (JP) 1995-03-15 EP disclosed