SCHEMBL7944103

SCHEMBL7944103

C#Cc1ccc2cc3ccccc3cc2c1C#C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.40
HSD17B10 Q99714 5/20 0.40
CYP1B1 Q16678 2/20 0.40
HIF1A Q16665 2/20 0.40
CYP1A1 P04798 1/20 0.34
KDM4E B2RXH2 3/20 0.34
GAA P10253 2/20 0.34
CYP1A2 P05177 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
ERBB2 P04626 1/20 0.33
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
ACHE P22303 1/20 0.33
AHR P35869 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HBB P68871 1/20 0.33
MEN1 O00255 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5431973 0.82 CYP2A6 (0.46) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
SCHEMBL31676618 0.82 CYP2A6 (0.46) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2
SCHEMBL27860879 0.79 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A1
SCHEMBL20699497 0.79 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP1B1HIF1AKDM4E
SCHEMBL27780597 0.78 ALDH1A1 (0.38) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A1
SCHEMBL30918302 0.78 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A1
SCHEMBL937286 0.78 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A1
SCHEMBL28776208 0.77 ALDH1A1 (0.45) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A1
SCHEMBL2834902 0.77 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP1B1HIF1ACYP1A1
SCHEMBL8952369 0.77 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP1B1HIF1AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0834499-B1 Process for the preparation of aromatic vinyl compounds DAINIPPON INK & CHEMICALS (JP) 2001-07-25 EP disclosed
EP-0834499-A1 Process for the preparation of aromatic vinyl compounds DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-04-08 EP disclosed