Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31676618 | 1.00 | CYP2A6 (0.46) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL21160352 | 0.86 | CA1 (0.47) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL7944103 | 0.82 | ALDH1A1 (0.40) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL2745875 | 0.81 | APP (0.41) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL2745872 | 0.81 | APP (0.41) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL23054105 | 0.77 | CYP2A6 (0.44) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL20529660 | 0.77 | PTPN22 (0.54) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL689190 | 0.77 | ALDH1A1 (0.44) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL21160351 | 0.77 | CYP2A6 (0.44) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL7940388 | 0.77 | PTPN22 (0.54) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155997-A1 | Organic compositions | HONEYWELL INTERNATIONAL INC. | 2007-07-05 | — | — | US | claimed |
| EP-1578839-A4 | ORGANIC COMPOSITIONS | HONEYWELL INT INC (US) | 2007-06-20 | — | — | EP | claimed |
| EP-1578839-A1 | ORGANIC COMPOSITIONS | Honeywell International, Inc. (US) | 2005-09-28 | — | — | EP | claimed |
| WO-2005010071-A1 | ORGANIC COMPOSITIONS | HONEYWELL INTERNATIONAL INC (US) | 2005-02-03 | — | — | WO | claimed |
| US-20070155997-A1 | Organic compositions | HONEYWELL INTERNATIONAL INC. | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155997-A1 | Organic compositions | AHR, PAH, POLL | CYP2A6 156/4885ALDH1A1 1188/4885HSD17B10 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.