SCHEMBL7944351

SCHEMBL7944351

COc1nc(C(Cl)Cl)c(Cl)c(OC)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7957470 0.78 CYP1A2 (0.34) CYP1A2
Penclomedine SCHEMBL188460 0.68 CYP1A2 (0.35) CYP1A2
Penclomedine SCHEMBL29431894 0.68 CYP1A2 (0.35) CYP1A2
SCHEMBL31277708 0.64 KDM4E (0.35)
SCHEMBL13880635 0.64 KDM4E (0.35)
SCHEMBL9432184 0.63 CYP1A2 (0.61) CYP1A2
SCHEMBL301807 0.61 CA1 (0.35)
SCHEMBL17302069 0.60 CYP1A2 (0.52) CYP1A2
SCHEMBL4373644 0.60 AMY1A (0.31)
SCHEMBL7607691 0.60 CCNA2 (0.47) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235761-B1 USING 3,5-DICHLORO-2-METHOXY-4-HYDROXY-6-(TRICHLOROMETHYL)PYRIDINE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2001-05-22 US disclosed