Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | COMT | P21964 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754955 | 0.90 | COMT (0.44) | HSP90AA1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL8385492 | 0.81 | TNKS (0.46) | TNKSTNKS2ATMWNT3ATYMP | |
| SCHEMBL7953052 | 0.81 | P2RX1 (0.39) | HSP90AA1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL7043221 | 0.80 | KMT2A (0.44) | HSP90AA1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL5755561 | 0.80 | MAPT (0.47) | HSP90AA1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL7943951 | 0.77 | TMPRSS4 (0.41) | HSP90AA1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL7944057 | 0.76 | ARF6 (0.37) | HSP90AA1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL7952535 | 0.73 | TNKS (0.43) | MAPTCYP2C9TSHRKCNMA1TNKS | |
| SCHEMBL7944370 | 0.72 | HSP90AA1 (0.53) | HSP90AA1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL5754718 | 0.71 | COMT (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271249-B1 | Diphenyl imidazoles as potassium channel modulators | BRISTOL-MYERS SQUIBB COMPANY | 2001-08-07 | — | — | US | disclosed |