Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL20471926 | 1.00 | GLRA1 (0.67) | — | |
| Glycine SCHEMBL29180544 | 1.00 | GLRA1 (0.67) | — | |
| Glycine SCHEMBL4942685 | 1.00 | GLRA1 (0.67) | — | |
| Glycine SCHEMBL7122600 | 0.90 | — | — | |
| Glycine SCHEMBL28263992 | 0.90 | GLRA1 (0.62) | — | |
| Lactic Acid SCHEMBL3253029 | 0.88 | TP53 (0.65) | — | |
| Glycine SCHEMBL5921300 | 0.87 | — | — | |
| Glycine SCHEMBL28337203 | 0.87 | — | — | |
| Glycerin SCHEMBL8821885 | 0.87 | OR51E2 (0.50) | — | |
| Lactic Acid SCHEMBL15441790 | 0.85 | TP53 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104874025-B | Novel Hollow Microparticles | 国玺干细胞应用技术股份有限公司 | 2018-03-09 | — | — | CN | disclosed |
| CN-104874025-A | Novel Hollow Microparticles | GWO XI STEM CELL APPLIED TECHNOLOGY CO LTD | 2015-09-02 | — | — | CN | disclosed |
| CN-1758900-B | Pharmaceutical composition | UNIVERSITY OF STRATHCLYDE (GB) | 2012-02-08 | — | — | CN | disclosed |
| CN-1758900-A | Pharmaceutical composition | UNIV STRATHCLYDE (GB) | 2006-04-12 | — | — | CN | disclosed |
| US-6242351-B1 | MULTISTAGE PROCESS OF SEMICONDUCTOR WAFERS AND WATER SLURRY | GENERAL ELECTRIC COMPANY | 2001-06-05 | — | — | US | disclosed |