Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL5921300 | 0.90 | — | — | |
| Glycine SCHEMBL4942685 | 0.90 | GLRA1 (0.67) | — | |
| Glycine SCHEMBL20471926 | 0.90 | GLRA1 (0.67) | — | |
| Glycine SCHEMBL7944810 | 0.90 | — | — | |
| Glycine SCHEMBL29180544 | 0.90 | GLRA1 (0.67) | — | |
| Glycine SCHEMBL28263992 | 0.88 | GLRA1 (0.62) | — | |
| Alanine SCHEMBL25189736 | 0.85 | GLRA1 (0.59) | — | |
| Alanine SCHEMBL1675385 | 0.85 | GLRA1 (0.59) | — | |
| D-Alanine SCHEMBL1537294 | 0.85 | GLRA1 (0.59) | — | |
| Alanine SCHEMBL2083490 | 0.85 | GLRA1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720485-B1 | METHOD OF ACTIVATING SOLUBLE CARBOHYDRATE USING NOVEL CYANYLATING REAGENTS FOR THE PRODUCTION OF IMMUNOGENIC CONSTRUCTS | JACKSON H M FOUND MILITARY MED (US) | 2003-11-19 | — | — | EP | disclosed |
| EP-0720485-A1 | METHOD OF ACTIVATING SOLUBLE CARBOHYDRATE USING NOVEL CYANYLATING REAGENTS FOR THE PRODUCTION OF IMMUNOGENIC CONSTRUCTS | HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE (US) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008348-A1 | METHOD OF ACTIVATING SOLUBLE CARBOHYDRATE USING NOVEL CYANYLATING REAGENTS FOR THE PRODUCTION OF IMMUNOGENIC CONSTRUCTS | HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE (US) | 1995-03-30 | — | — | WO | disclosed |