Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 5/20 | 0.38 |
| ▸ | REN | P00797 | 4/20 | 0.38 |
| ▸ | PEPD | P12955 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20388035 | 0.86 | DPP4 (0.40) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL3726967 | 0.84 | DPP4 (0.42) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL24051779 | 0.82 | ELANE (0.42) | ELANEACERENPEPDKDM4E | |
| SCHEMBL8144172 | 0.82 | ELANE (0.54) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL14421202 | 0.81 | ELANE (0.42) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL12812283 | 0.81 | DPP4 (0.39) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8055611 | 0.80 | ELANE (0.42) | ELANEACEF2 | |
| SCHEMBL806180 | 0.80 | ELANE (0.42) | ELANEACEF2 | |
| SCHEMBL14232792 | 0.80 | ELANE (0.42) | ELANEACEF2 | |
| SCHEMBL15705223 | 0.79 | XIAP (0.49) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045266-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | INTERMUNE, INC. (US) | 2010-04-22 | — | — | WO | disclosed |