Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.59 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.57 |
| ▸ | DPP4 | P27487 | 2/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.55 |
| ▸ | CCR6 | P51684 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945013 | 1.00 | ANPEP (0.59) | ANPEPDPP8DPP7SLC1A3SLC1A1 | |
| SCHEMBL18560009 | 0.93 | ANPEP (0.61) | ANPEPDPP8DPP7SLC1A3SLC1A1 | |
| SCHEMBL453671 | 0.90 | DPP8 (0.69) | ANPEPDPP8DPP7SLC1A3SLC1A1 | |
| SCHEMBL464672 | 0.90 | DPP8 (0.69) | ANPEPDPP8DPP7SLC1A3SLC1A1 | |
| SCHEMBL5816135 | 0.90 | DPP8 (0.69) | ANPEPDPP8DPP7SLC1A3SLC1A1 | |
| SCHEMBL7944789 | 0.90 | SLC1A3 (0.56) | ANPEPDPP8DPP7SLC1A3SLC1A1 | |
| SCHEMBL7947977 | 0.90 | SLC1A3 (0.56) | ANPEPDPP8DPP7SLC1A3SLC1A1 | |
| Hydrochloric Acid SCHEMBL7297967 | 0.89 | DPP8 (0.68) | ANPEPDPP8DPP7SLC1A3SLC1A1 | |
| Hydrochloric Acid SCHEMBL18770783 | 0.89 | DPP8 (0.68) | ANPEPDPP8DPP7SLC1A3SLC1A1 | |
| SCHEMBL7028548 | 0.89 | DPP8 (0.68) | ANPEPDPP8DPP7SLC1A3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258931-B1 | SYNTHESIZING DEOXYHYPUSINE DERIVATIVE BY USING ESTER OF DIPROTECTED LYSINE, DEBLOCKING ONE NITROGEN, CONDENSING WITH 3-CYANOPROPANAL, REDUCING TO A TRIAMINE, PROTECTING FREE AMINO GROUPS, DEBLOCKING AGAIN, AND ACYLATING THE FREE AMINO GROUP | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2001-07-10 | — | — | US | disclosed |