Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16261916 | 0.87 | DPP4 (0.41) | DPP4DPP7MAOAMAOBADRB1 | |
| SCHEMBL8498489 | 0.85 | DPP4 (0.41) | DPP4DPP7ADRB1HTR2AHTR2C | |
| SCHEMBL13860379 | 0.85 | DPP4 (0.43) | DPP4DPP7MAOAMAOBHTR2A | |
| SCHEMBL2386164 | 0.85 | DPP4 (0.47) | DPP4DPP7HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL28773228 | 0.84 | DPP4 (0.46) | DPP4DPP7HTR2AHTR2CHTR2B | |
| SCHEMBL1693684 | 0.83 | HTR2C (0.42) | DPP4DPP7MAOAMAOBADRB1 | |
| SCHEMBL1720843 | 0.83 | NSD2 (0.44) | DPP4DPP7HTR2AHTR2CHTR2B | |
| SCHEMBL16462634 | 0.82 | MAOA (0.42) | DPP4DPP7MAOAMAOBHTR2A | |
| SCHEMBL14461955 | 0.82 | KMT2A (0.44) | DPP4DPP7MAOAMAOB | |
| Hydrochloric Acid SCHEMBL29737099 | 0.81 | HTR2A (0.38) | DPP4DPP7HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941922-A1 | INHIBITORS OF RAF KINASES | Kinnate Biopharma Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| EP-2405973-A2 | THIAZOLOPYRIMIDINE MODULATORS AS IMMUNOSUPPRESSIVE AGENTS | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2012-01-18 | — | — | EP | disclosed |