Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16261916 | 0.87 | DPP4 (0.41) | DPP4DPP7HTR2AHTR2CHTR2B | |
| SCHEMBL794507 | 0.85 | DPP4 (0.43) | DPP4DPP7HTR2AHTR2CHTR2B | |
| SCHEMBL8496002 | 0.85 | DPP4 (0.45) | DPP4DPP7HTR2AHTR2CHTR2B | |
| SCHEMBL14461955 | 0.82 | KMT2A (0.44) | DPP4DPP7MEN1KMT2A | |
| SCHEMBL28956573 | 0.79 | ADRB1 (0.37) | DPP4DPP7HTR2AHTR2CHTR2B | |
| SCHEMBL8498209 | 0.77 | KMT2A (0.46) | ADRB1MEN1CYP2D6KMT2A | |
| SCHEMBL3338258 | 0.75 | LMNA (0.44) | DPP4DPP7HTR2AHTR2CHTR2B | |
| SCHEMBL6026785 | 0.74 | ADRB1 (0.43) | HTR2CADRB1ADCY5 | |
| SCHEMBL7467909 | 0.74 | DPP4 (0.54) | DPP4DPP7HTR2AHTR2CHTR2B | |
| SCHEMBL3449047 | 0.73 | ADRB1 (0.39) | HTR2AHTR2CHTR2BADRB1ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552417-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0528312-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-07-16 | — | — | EP | disclosed |