Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7534922 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL9412839 | 0.66 | KDM4E (0.39) | — | |
| Hydrochloric Acid SCHEMBL7711388 | 0.65 | METAP1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL5079601 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL9412824 | 0.64 | CYP17A1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL9412842 | 0.64 | HSP90AA1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL5081154 | 0.63 | METAP1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL5077701 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL7644406 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL5083360 | 0.61 | PGR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773239-B1 | Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems | FINA TECHNOLOGY (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-0773239-A2 | Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems | FINA TECHNOLOGY, INC. (US) | 1997-05-14 | — | — | EP | disclosed |
| EP-0773238-A2 | Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems | FINA TECHNOLOGY, INC. (US) | 1997-05-14 | — | — | EP | disclosed |
| EP-0577581-A2 | Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems | FINA TECHNOLOGY, INC. (US) | 1994-01-05 | — | — | EP | disclosed |