SCHEMBL7945247

SCHEMBL7945247

C=Cc1cccc(CC)c1[SiH3]

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.40
GABRB2 P47870 4/20 0.40
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAOA P21397 1/20 0.31
PIM1 P11309 1/20 0.30
PIM3 Q86V86 1/20 0.30
CRHR1 P34998 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4911768 0.80 GABRA1 (0.46) GABRA1GABRB2ALDH1A1LMNASMN1; SMN2
SCHEMBL420437 0.79 GABRA1 (0.43) GABRA1GABRB2ALDH1A1LMNASMN1; SMN2
SCHEMBL14959 0.79 ALDH1A1 (0.44) GABRA1GABRB2ALDH1A1LMNAL3MBTL1
SCHEMBL29749448 0.79 ALDH1A1 (0.44) GABRA1GABRB2ALDH1A1LMNAL3MBTL1
SCHEMBL27516529 0.79 ALDH1A1 (0.44) GABRA1GABRB2ALDH1A1LMNAL3MBTL1
SCHEMBL28256638 0.78 GABRA1 (0.55) GABRA1GABRB2L3MBTL1PDK2
SCHEMBL29407303 0.78 GABRA1 (0.41) GABRA1GABRB2ALDH1A1LMNASMN1; SMN2
SCHEMBL110775 0.78 GABRA1 (0.41) GABRA1GABRB2ALDH1A1LMNASMN1; SMN2
SCHEMBL59712 0.78 GABRA1 (0.41) GABRA1GABRB2ALDH1A1LMNASMN1; SMN2
SCHEMBL28802097 0.77 ALDH1A1 (0.43) GABRA1GABRB2ALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001046276-A1 METALLOCENE CATALYSTS HAVING MULTI-NUCLEAR CONSTRAINED GEOMETRY AND ETHYLENE/AROMATIC VINYL COMPOUND CO-POLYMERS PREPARED BY USING THE SAME SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2001-06-28 WO disclosed