Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | RXRG | P48443 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211820 | 0.91 | CA12 (0.45) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL3125823 | 0.87 | TSHR (0.52) | HTTRXRARXRBRXRGTSHR | |
| SCHEMBL3215147 | 0.87 | TSHR (0.46) | RXRARXRBRXRGPOLBCASP6 | |
| SCHEMBL2908361 | 0.87 | MKNK1 (0.41) | CYP1A2MEN1KMT2ARXRARXRB | |
| SCHEMBL2902512 | 0.86 | LMNA (0.48) | HTTRAB9ARXRARXRBRXRG | |
| SCHEMBL3216019 | 0.86 | RXRA (0.49) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL3125356 | 0.85 | RXRA (0.39) | HTTRAB9AKMT2ARXRARXRB | |
| SCHEMBL3131039 | 0.85 | RXRA (0.39) | HTTRAB9AMEN1KMT2ARXRA | |
| SCHEMBL3213634 | 0.85 | CA12 (0.35) | HTTRAB9AMEN1KMT2ARXRA | |
| SCHEMBL16160340 | 0.83 | KMT2A (0.39) | CYP1A2MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |