Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7641470 | 0.79 | BRD4 (0.34) | HTR6HTR2ASIGMAR1 | |
| Ethane SCHEMBL8628959 | 0.77 | BRD4 (0.33) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL29215999 | 0.76 | HTR2A (0.36) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL8853875 | 0.76 | SIGMAR1 (0.36) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL29479969 | 0.76 | SIGMAR1 (0.36) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL30533389 | 0.75 | HTR2A (0.39) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL4846521 | 0.75 | BRD4 (0.32) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL6054094 | 0.74 | HTR2A (0.35) | HTR6HTR2ASIGMAR1 | |
| Ethane SCHEMBL8634251 | 0.73 | HTR2A (0.37) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL6732035 | 0.73 | BRD4 (0.31) | HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044509-A1 | Haloaryl containing group 13 substituents on bridged metallocene polyolefin catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-11-22 | — | — | US | disclosed |
| EP-1144467-A1 | HALOARYL CONTAINING GROUP 13 SUBSTITUENTS ON BRIDGED METALLOCENE POLYOLEFIN CATALYSTS | Univation Technologies LLC (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000037513-A1 | HALOARYL CONTAINING GROUP 13 SUBSTITUENTS ON BRIDGED METALLOCENE POLYOLEFIN CATALYSTS | UNIVATION TECHNOLOGIES, LLC (US) | 2000-06-29 | — | — | WO | disclosed |