Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 4/20 | 0.38 |
| ▸ | AXL | P30530 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12831059 | 0.85 | NFKB1 (0.39) | NFKB1NFKB2RELAGLSCDK8 | |
| SCHEMBL1950495 | 0.79 | MEN1 (0.49) | NFKB1NFKB2RELAGLSMEN1 | |
| SCHEMBL7955760 | 0.78 | KMT2A (0.43) | NFKB1NFKB2RELAGLSMEN1 | |
| SCHEMBL7950069 | 0.78 | NFKB1 (0.42) | NFKB1NFKB2RELAGLSMEN1 | |
| SCHEMBL2180368 | 0.74 | MEN1 (0.47) | NFKB1NFKB2RELACDK8AXL | |
| SCHEMBL7951000 | 0.73 | NFKB1 (0.42) | NFKB1NFKB2RELAGLSMEN1 | |
| SCHEMBL1950210 | 0.71 | ANO1 (0.55) | GLSANO1 | |
| SCHEMBL27260532 | 0.70 | HDAC6 (0.54) | NFKB1NFKB2RELAGLSABL1 | |
| SCHEMBL1954085 | 0.69 | ANO1 (0.53) | GLSMEN1KMT2AANO1 | |
| SCHEMBL12271221 | 0.69 | MEN1 (0.56) | GLSMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025295-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-04 | — | — | WO | disclosed |