Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 10/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12831055 | 0.84 | NFKB1 (0.42) | NFKB1NFKB2RELAGLSALDH1A1 | |
| SCHEMBL1950495 | 0.83 | MEN1 (0.49) | NFKB1NFKB2RELAGLSALDH1A1 | |
| SCHEMBL7955760 | 0.81 | KMT2A (0.43) | NFKB1NFKB2RELAGLSALDH1A1 | |
| SCHEMBL7945422 | 0.78 | NFKB1 (0.41) | NFKB1NFKB2RELAGLSALDH1A1 | |
| SCHEMBL7951000 | 0.76 | NFKB1 (0.42) | NFKB1NFKB2RELAGLSALDH1A1 | |
| SCHEMBL1950210 | 0.76 | ANO1 (0.55) | GLSANO1 | |
| SCHEMBL12831001 | 0.73 | NFKB1 (0.42) | NFKB1NFKB2RELAGLSALDH1A1 | |
| SCHEMBL12271719 | 0.73 | ANO1 (0.57) | MEN1KMT2AANO1 | |
| SCHEMBL1954085 | 0.73 | ANO1 (0.53) | GLSMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL12271221 | 0.73 | MEN1 (0.56) | GLSALDH1A1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025295-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-04 | — | — | WO | disclosed |