Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943336 | 0.84 | KDM4E (0.41) | KDM4ERAB9AMEN1NPC1ALDH1A1 | |
| SCHEMBL8160844 | 0.84 | KDM4E (0.40) | KDM4ERAB9AMEN1NPC1ALDH1A1 | |
| SCHEMBL7943311 | 0.83 | KDM4E (0.35) | KDM4ERAB9AMEN1NPC1ALDH1A1 | |
| SCHEMBL7934589 | 0.81 | NPC1 (0.37) | RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL22607471 | 0.80 | NPC1 (0.36) | RAB9ANPC1 | |
| SCHEMBL7945473 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL22572767 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL8823191 | 0.71 | KDM4E (0.38) | KDM4ERAB9AMEN1NPC1ALDH1A1 | |
| SCHEMBL7943320 | 0.71 | KDM4E (0.38) | KDM4ERAB9AMEN1NPC1ALDH1A1 | |
| SCHEMBL7941151 | 0.71 | KDM4E (0.50) | KDM4ERAB9AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316558-B1 | POLYMERIZING OLEFIN USING CATALYST COMPRISING TRANSITION METAL COMPOUND, COMPOUND CAPABLE OF A REACTING WITH TRANSITION METAL COMPOUND TO FORM A CATIONIC TRANSITION METAL COMPOUND, ORGANOMETALLIC TO FORM POLYOLEFIN | TOSOH CORPORATION (JP) | 2001-11-13 | — | — | US | disclosed |