Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.33 |
| ▸ | PDE4A | P27815 | 6/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790567 | 0.71 | PDE10A (0.39) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL909354 | 0.70 | PDE10A (0.64) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL27945167 | 0.68 | PDE10A (0.37) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL22340924 | 0.67 | TDP2 (0.38) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL22340274 | 0.67 | TDP2 (0.38) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL22341027 | 0.67 | TDP2 (0.38) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL789951 | 0.66 | PDE10A (0.34) | PDE10A | |
| SCHEMBL4421489 | 0.65 | PDE10A (0.83) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL909717 | 0.64 | CHRM3 (0.43) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL19679965 | 0.64 | PDE10A (0.45) | PDE10ACHRM3PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211190-B1 | Pyrimidine derivatives, process and intermediate products for their preparation and pesticides or fungicides containing these derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-03 | — | — | US | disclosed |
| CN-1187814-A | (hetero) aryloxy-, -thio-and-aminocrotonates, preparation and use thereof | BASF AG (DE) | 1998-07-15 | — | — | CN | disclosed |
| CN-1161687-A | Phenylacetic acid alkyl esters | BASF AG (DE) | 1997-10-08 | — | — | CN | disclosed |