Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5554528 | 0.78 | KMT2A (0.50) | MEN1POLBMAPTKMT2ATDP1 | |
| SCHEMBL1558220 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP3A4L3MBTL1TSHR | |
| SCHEMBL3790255 | 0.75 | MEN1 (0.56) | MEN1MAPTKMT2AALDH1A1HSD17B10 | |
| SCHEMBL398444 | 0.74 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL2087211 | 0.74 | ALDH1A1 (0.57) | MEN1MAPTKMT2ATDP1ALDH1A1 | |
| SCHEMBL10945125 | 0.74 | CYP1A2 (0.56) | MEN1POLBMAPTKMT2ATDP1 | |
| SCHEMBL3786946 | 0.73 | ALDH1A1 (0.52) | MEN1POLBMAPTKMT2ATDP1 | |
| SCHEMBL1558917 | 0.73 | ALDH1A1 (0.50) | MAPTALDH1A1HSD17B10CYP3A4L3MBTL1 | |
| SCHEMBL3794304 | 0.73 | BCHE (0.51) | MEN1POLBMAPTKMT2ATDP1 | |
| SCHEMBL5745573 | 0.72 | ALDH1A1 (0.45) | MEN1POLBMAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |