Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.42 |
| ▸ | RHEB | Q15382 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683631 | 0.83 | MAOA (0.59) | KMT2AMEN1MAOBMAOAMAPT | |
| SCHEMBL11292862 | 0.81 | HTT (0.53) | KMT2AMEN1MAOBMAOAMAPT | |
| SCHEMBL6658670 | 0.80 | THRB (0.57) | KMT2AMEN1MAOBMAOALTA4H | |
| SCHEMBL3228597 | 0.80 | TDP1 (0.50) | KMT2AMEN1MAOBMAOATDP1 | |
| SCHEMBL10701332 | 0.80 | MAPT (0.42) | KMT2AMEN1MAOBMAPTPOLB | |
| SCHEMBL13556591 | 0.79 | NPBWR1 (0.44) | KMT2AMEN1MAPTPOLBTDP1 | |
| Hydrochloric Acid SCHEMBL29965433 | 0.79 | ALDH1A1 (0.52) | KMT2AMEN1MAPTTDP1CYP3A4 | |
| SCHEMBL10945125 | 0.79 | CYP1A2 (0.56) | KMT2AMEN1MAOBMAOANPC1 | |
| SCHEMBL7945574 | 0.78 | MEN1 (0.48) | KMT2AMEN1MAOBMAOAMAPT | |
| SCHEMBL9645022 | 0.78 | LTA4H (0.52) | KMT2AMEN1MAOBMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |
| EP-1147093-B1 | SUBSTITUTED BICYCLIC DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PROD INC (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1137632-B1 | THIOUREA INHIBITORS OF HERPES VIRUSES | WYETH CORP (US) | 2004-07-28 | — | — | EP | disclosed |
| EP-1137645-B1 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | WYETH CORP (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20030186995-A1 | Substituted bicyclic derivatives useful as anticancer agents | PFIZER INC. | 2003-10-02 | — | — | US | disclosed |
| US-6555561-B2 | N-(5-((((5-Chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)-amino)-2 -pyridinyl)-2-methylbenzamide, for example; inhibiting replication of a herpes virus | WYETH | 2003-04-29 | — | — | US | disclosed |
| US-6541481-B2 | A quinazoline compound | PFIZER INC | 2003-04-01 | — | — | US | disclosed |
| US-20030036653-A1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | AMERICAN HOME PRODUCTS CORPORATION | 2003-02-20 | — | — | US | disclosed |
| US-6462055-B2 | VIRICIDES | WYETH | 2002-10-08 | — | — | US | disclosed |
| EP-1144397-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-0101990-A1 | N-benzoyl-N'-phenoxyphenyl ureas, process for their preparation and their use as pesticides | BASF Aktiengesellschaft (DE) | 1984-03-07 | — | — | EP | disclosed |
| US-4429156-A | Process for the preparation of m-halogen-substituted anilines | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| US-4418213-A | HYDRODEHALOGENATION LEWIS ACID AND NOBLE METAL CATALYSTS | RHONE-POULENC AGROCHIMIE (FR) | 1983-11-29 | — | — | US | disclosed |
| EP-0069907-A2 | Process for preparing m-chloro-substituted anilines | BAYER AG (DE) | 1983-01-19 | — | — | EP | disclosed |
| US-4351959-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-09-28 | — | — | US | disclosed |
| US-4340759-A | Process for the preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-07-20 | — | — | US | disclosed |
| EP-0051782-A1 | Process for the manufacture of m-halogenated anilines | BAYER AG (DE) | 1982-05-19 | — | — | EP | disclosed |
| US-4324914-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-04-13 | — | — | US | disclosed |
| US-4193937-A | DECHLORINATION OF CHLOROANILINES, SELECTIVE HYDROGENATION CATALYSTS OF NOBLE METAL AND SULFUR | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-18 | — | — | US | disclosed |
| US-4085141-A | Process for the preparation of anilines meta-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186995-A1 | Substituted bicyclic derivatives useful as anticancer agents | CCNA1, MCL1, RCC1 | KMT2A 2888/4885MEN1 911/4885MAOB 2762/4885 |
| US-20030036653-A1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | HAVCR2, CCR6, CXCR6 | KMT2A 2957/4885MEN1 4810/4885MAOB 3776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.