Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666509 | 0.75 | IDO1 (0.41) | ANPEPIDO1PNMT | |
| SCHEMBL8699123 | 0.72 | ALDH1A1 (0.37) | DRD3 | |
| SCHEMBL24890476 | 0.71 | IDO1 (0.43) | ANPEPIDO1PNMT | |
| SCHEMBL5724797 | 0.71 | GRM7 (0.41) | IDO1DRD3 | |
| SCHEMBL28071032 | 0.71 | PRMT5 (0.33) | IDO1 | |
| SCHEMBL22968842 | 0.67 | HTR2A (0.38) | ANPEPIDO1ADRA2A | |
| SCHEMBL1168633 | 0.67 | IDO1 (0.39) | ANPEPIDO1 | |
| SCHEMBL27518244 | 0.67 | IDO1 (0.39) | ANPEPIDO1 | |
| SCHEMBL23874539 | 0.67 | IDO1 (0.39) | IDO1DRD3 | |
| SCHEMBL16595720 | 0.67 | TSHR (0.39) | ANPEPIDO1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172109-B1 | SIDE EFFECT REDUCTION; ADMINISTERING TOPICALLY | ALCON LABORATORIES, INC. | 2001-01-09 | — | — | US | disclosed |
| EP-0968183-A2 | 13-THIA PROSTAGLANDINS FOR USE IN GLAUCOMA THERAPY | ALCON LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998039293-A2 | 13-THIA PROSTAGLANDINS FOR USE IN GLAUCOMA THERAPY | ALCON LABORATORIES, INC. (US) | 1998-09-11 | — | — | WO | disclosed |