Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959194 | 0.80 | KCNA3 (0.69) | CYP2A6KCNA3CYP3A4ALOX15KCNA5 | |
| SCHEMBL8798424 | 0.79 | CYP2A6 (0.66) | CYP2A6KCNA3CYP3A4ALOX15KCNA5 | |
| SCHEMBL7954068 | 0.78 | MCL1 (0.52) | MCL1 | |
| SCHEMBL7953867 | 0.78 | MCL1 (0.52) | MCL1 | |
| SCHEMBL7945714 | 0.76 | CA12 (0.56) | MAOB | |
| SCHEMBL9120110 | 0.76 | CYP2A6 (0.64) | CYP2A6KCNA3CYP3A4ALOX15KCNA5 | |
| SCHEMBL4136788 | 0.73 | CYP2A6 (0.42) | CYP2A6KCNA3CYP3A4ALOX15MCL1 | |
| SCHEMBL7954015 | 0.73 | MAOB (0.55) | MAOB | |
| SCHEMBL14027459 | 0.70 | MAPK1 (0.39) | — | |
| SCHEMBL11651179 | 0.69 | KCNA3 (0.92) | CYP2A6KCNA3CYP3A4ALOX15KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449602-A | Polynucleotides | AMOCO CORPORATION (US) | 1995-09-12 | — | — | US | claimed |
| EP-0324616-B1 | Template-directed photoligation | AMOCO CORP (US) | 1995-03-29 | — | — | EP | claimed |
| EP-0324616-A2 | Template-directed photoligation | AMOCO CORPORATION (US) | 1989-07-19 | — | — | EP | claimed |
| US-6306587-B1 | APPARATUS OF VESSEL FOR RECEIVING SAMPLE AND TWO PROBES, EACH HAVING FUNCTIONAL GROUPS CAPABLE OF REACTING WITH EACH OTHER TO FORM COVALENT BOND; LIGHT SOURCE TO ACTIVATE GROUPS; AND DETECTOR TO DETECT REACTION PRODUCT | VYSIS, INC. | 2001-10-23 | — | — | US | disclosed |
| US-5686243-A | DETECTING POLYNUCLEOTIDE SEQUENCES; HYBRIDIZATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-11-11 | — | — | US | disclosed |
| US-5449602-A | Polynucleotides | AMOCO CORPORATION (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0324616-B1 | Template-directed photoligation | AMOCO CORP (US) | 1995-03-29 | — | — | EP | disclosed |
| EP-0324616-A2 | Template-directed photoligation | AMOCO CORPORATION (US) | 1989-07-19 | — | — | EP | disclosed |