Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2802894 | 0.88 | ALDH1A1 (0.62) | KDM4EKMT2AALDH1A1MAPTAR | |
| SCHEMBL29270309 | 0.84 | MAOA (0.65) | MAOBMAOAKDM4EKMT2AALDH1A1 | |
| SCHEMBL7945714 | 0.83 | CA12 (0.56) | MAOBMAOAKDM4EKMT2AALDH1A1 | |
| SCHEMBL9204774 | 0.81 | KMT2A (0.66) | MAOBMAOAKDM4EKMT2AALDH1A1 | |
| SCHEMBL29677221 | 0.81 | KMT2A (0.66) | MAOBMAOAKDM4EKMT2AALDH1A1 | |
| SCHEMBL6588397 | 0.77 | KMT2A (0.61) | MAOBMAOAKDM4EKMT2AALDH1A1 | |
| SCHEMBL28026514 | 0.77 | MAOB (0.70) | MAOBMAOAKDM4EKMT2AALDH1A1 | |
| SCHEMBL6591353 | 0.77 | MAOB (0.70) | MAOBMAOAKDM4EKMT2AALDH1A1 | |
| SCHEMBL10063475 | 0.77 | MAOB (0.74) | MAOBMAOAKDM4EKMT2AALDH1A1 | |
| SCHEMBL8093680 | 0.76 | ALDH1A1 (0.67) | MAOBMAOAKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449602-A | Polynucleotides | AMOCO CORPORATION (US) | 1995-09-12 | — | — | US | claimed |
| EP-0324616-B1 | Template-directed photoligation | AMOCO CORP (US) | 1995-03-29 | — | — | EP | claimed |
| US-6306587-B1 | APPARATUS OF VESSEL FOR RECEIVING SAMPLE AND TWO PROBES, EACH HAVING FUNCTIONAL GROUPS CAPABLE OF REACTING WITH EACH OTHER TO FORM COVALENT BOND; LIGHT SOURCE TO ACTIVATE GROUPS; AND DETECTOR TO DETECT REACTION PRODUCT | VYSIS, INC. | 2001-10-23 | — | — | US | disclosed |
| US-5686243-A | DETECTING POLYNUCLEOTIDE SEQUENCES; HYBRIDIZATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-11-11 | — | — | US | disclosed |
| US-5449602-A | Polynucleotides | AMOCO CORPORATION (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0324616-B1 | Template-directed photoligation | AMOCO CORP (US) | 1995-03-29 | — | — | EP | disclosed |
| EP-0324616-A2 | Template-directed photoligation | AMOCO CORPORATION (US) | 1989-07-19 | — | — | EP | disclosed |