Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.48 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.48 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.48 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.48 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.48 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.48 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.48 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.48 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.48 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.48 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.48 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.48 |
| ▸ | NDUFS6 | O75380 | 1/20 | 0.48 |
| ▸ | NDUFB1 | O75438 | 1/20 | 0.48 |
| ▸ | NDUFS3 | O75489 | 1/20 | 0.48 |
| ▸ | NDUFB6 | O95139 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953867 | 1.00 | MCL1 (0.52) | MCL1KDM4EGLAPOLBNDUFS8 | |
| SCHEMBL7945714 | 0.83 | CA12 (0.56) | KDM4EPOLBCA9CA12CA1 | |
| SCHEMBL7959441 | 0.81 | MCL1 (0.58) | MCL1KDM4EGLAPOLBNDUFS8 | |
| SCHEMBL7953897 | 0.81 | MCL1 (0.64) | MCL1KDM4EGLAPOLBNDUFS8 | |
| SCHEMBL7954077 | 0.81 | MCL1 (0.64) | MCL1KDM4EGLAPOLBNDUFS8 | |
| SCHEMBL7945707 | 0.78 | CYP2A6 (0.54) | MCL1 | |
| SCHEMBL8807776 | 0.77 | MCL1 (0.69) | MCL1KDM4EGLAPOLBNDUFS8 | |
| SCHEMBL8807781 | 0.77 | MCL1 (0.69) | MCL1KDM4EGLAPOLBNDUFS8 | |
| SCHEMBL23124362 | 0.76 | KMT2A (0.54) | KDM4EPOLBMEN1ALDH1A1HPGD | |
| SCHEMBL8809932 | 0.76 | MCL1 (0.71) | MCL1KDM4EGLAPOLBNDUFS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449602-A | Polynucleotides | AMOCO CORPORATION (US) | 1995-09-12 | — | — | US | claimed |
| EP-0324616-B1 | Template-directed photoligation | AMOCO CORP (US) | 1995-03-29 | — | — | EP | claimed |
| EP-0324616-A2 | Template-directed photoligation | AMOCO CORPORATION (US) | 1989-07-19 | — | — | EP | claimed |
| US-6306587-B1 | APPARATUS OF VESSEL FOR RECEIVING SAMPLE AND TWO PROBES, EACH HAVING FUNCTIONAL GROUPS CAPABLE OF REACTING WITH EACH OTHER TO FORM COVALENT BOND; LIGHT SOURCE TO ACTIVATE GROUPS; AND DETECTOR TO DETECT REACTION PRODUCT | VYSIS, INC. | 2001-10-23 | — | — | US | disclosed |
| US-5686243-A | DETECTING POLYNUCLEOTIDE SEQUENCES; HYBRIDIZATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-11-11 | — | — | US | disclosed |
| US-5449602-A | Polynucleotides | AMOCO CORPORATION (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0324616-B1 | Template-directed photoligation | AMOCO CORP (US) | 1995-03-29 | — | — | EP | disclosed |
| EP-0324616-A2 | Template-directed photoligation | AMOCO CORPORATION (US) | 1989-07-19 | — | — | EP | disclosed |