Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319278 | 1.00 | KMT2A (0.52) | KMT2ANPC1MAPTMEN1MAPK1 | |
| SCHEMBL9319273 | 1.00 | KMT2A (0.52) | KMT2ANPC1MAPTMEN1MAPK1 | |
| SCHEMBL3486388 | 0.81 | NPC1 (0.65) | KMT2ANPC1MAPTMEN1MAPK1 | |
| SCHEMBL9297310 | 0.81 | NPC1 (0.65) | KMT2ANPC1MAPTMEN1MAPK1 | |
| SCHEMBL9297312 | 0.81 | NPC1 (0.65) | KMT2ANPC1MAPTMEN1MAPK1 | |
| SCHEMBL8642223 | 0.80 | MAPT (0.64) | MAPTALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL27705845 | 0.80 | NPC1 (0.48) | KMT2ANPC1MAPTMEN1MAPK1 | |
| SCHEMBL5025416 | 0.79 | MAPT (0.51) | KMT2ANPC1MAPTMEN1MAPK1 | |
| SCHEMBL5496015 | 0.79 | KMT2A (0.55) | KMT2ANPC1MAPTMEN1MAPK1 | |
| SCHEMBL11697720 | 0.77 | ALDH1A1 (0.50) | KMT2ANPC1MAPTMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255461-B1 | IMMUNOGLOBULIN; FOR USE AS A DIAGNOSTIC AND THERAPEUTIC TOOL IN THE TREATMENT OF MAMMALIAN DEFECTS | MOSBACH KLAUS (SE) | 2001-07-03 | — | — | US | disclosed |
| US-5858296-A | A BIOLOGICALLY ACTIVE MOLECULE FORMED BY POLYMERIZATION OF FUNCTIONAL MONOMERS AROUND A TEMPLATE MOLECULE THAT EXHIBITS DRUG ACTIVITY, REMOVAL OF TEMPLATE AND POLYMERIZATION OF SECOND CLASS OF MONOMER IN THE VOIDS LEFT BY TEMPLATE | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1999-01-12 | — | — | US | disclosed |
| US-5630978-A | POLYMERIZATION OF FUNCTIONAL MONOMERS AROUND A BIOLOGICALLY ACTIVE TEMPLATE MOLECULE, REMOVAL OF TEMPLATE TO LEAVE A VOID, THEN POLYMERIZATION OF OTHER MONOMER(S) IN THE VOID | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1997-05-20 | — | — | US | disclosed |
| WO-1996040822-A1 | PREPARATION OF BIOLOGICALLY ACTIVE MOLECULES BY MOLECULAR IMPRINTING | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (US) | 1996-12-19 | — | — | WO | disclosed |