Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19872891 | 0.89 | KDM4A (0.34) | CNR2KDM4AL3MBTL1KLKB1HRH3 | |
| SCHEMBL7948567 | 0.89 | KDM4A (0.34) | CNR2KDM4AL3MBTL1KLKB1HRH3 | |
| SCHEMBL10315062 | 0.85 | KDM4A (0.39) | CNR2KDM4AL3MBTL1KDM4ELMNA | |
| SCHEMBL18078935 | 0.83 | KDM4E (0.40) | KDM4AL3MBTL1KLKB1CA12CA2 | |
| SCHEMBL3583656 | 0.83 | KDM4A (0.40) | KDM4AL3MBTL1HRH3KDM4ELMNA | |
| SCHEMBL21129147 | 0.82 | HDAC1 (0.39) | KDM4AL3MBTL1KLKB1KDM4ELMNA | |
| SCHEMBL3586130 | 0.81 | KDM4A (0.40) | KDM4AL3MBTL1KDM4ELMNANAMPT | |
| SCHEMBL9978510 | 0.77 | HDAC3 (0.51) | CNR2CA12CA1CA2CA9 | |
| SCHEMBL6468245 | 0.76 | KDM4A (0.42) | KDM4AL3MBTL1CA12CA1CA2 | |
| SCHEMBL3798888 | 0.74 | KDM4A (0.40) | KDM4AL3MBTL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010009334-A1 | METHOD FOR PREPARING LARGAZOLE ANALOGS AND USES THEREOF | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-01-21 | — | — | WO | disclosed |