Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.43 |
| ▸ | AKT1 | P31749 | 5/20 | 0.40 |
| ▸ | MTOR | P42345 | 5/20 | 0.40 |
| ▸ | FBP1 | P09467 | 2/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938046 | 0.82 | AKT1 (0.37) | AKT1MTORFBP1ALDH1A1TSHR | |
| SCHEMBL7944871 | 0.78 | AKT1 (0.38) | ADORA2AAKT1MTORALDH1A1TSHR | |
| SCHEMBL7937482 | 0.78 | CYP1A2 (0.46) | AKT1MTORALDH1A1TSHR | |
| SCHEMBL7937497 | 0.77 | AKT1 (0.41) | AKT1MTORALDH1A1TSHR | |
| SCHEMBL7938419 | 0.77 | AKT1 (0.41) | AKT1MTORALDH1A1TSHR | |
| SCHEMBL7938180 | 0.77 | AKT1 (0.41) | AKT1MTORALDH1A1TSHR | |
| SCHEMBL7943737 | 0.76 | CYP1A2 (0.57) | AKT1MTORALDH1A1TSHR | |
| SCHEMBL7946948 | 0.76 | CYP1A2 (0.40) | AKT1MTORALDH1A1TSHR | |
| SCHEMBL3227759 | 0.75 | ALDH1A1 (0.39) | ADORA2AAKT1MTORALDH1A1TSHR | |
| SCHEMBL7938293 | 0.74 | CYP1A2 (0.48) | AKT1MTORALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008775-A1 | AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |