Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 8/20 | 0.38 |
| ▸ | METAP1 | P53582 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415889 | 0.86 | ALOX15 (0.44) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL1415713 | 0.86 | ALOX15 (0.44) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL1415988 | 0.86 | ALOX15 (0.44) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL1415500 | 0.86 | ALOX15 (0.44) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL4053926 | 0.86 | ALOX15 (0.44) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL6009385 | 0.82 | ALOX15 (0.44) | ALOX15ALDH1A1LMNAHSD17B10CYP2D6 | |
| SCHEMBL2561165 | 0.79 | TSHR (0.50) | ALOX15ALDH1A1TSHRLMNAHSD17B10 | |
| SCHEMBL5792485 | 0.79 | TSHR (0.50) | ALOX15ALDH1A1TSHRLMNAHSD17B10 | |
| SCHEMBL13890615 | 0.79 | TSHR (0.50) | ALOX15ALDH1A1TSHRLMNAHSD17B10 | |
| SCHEMBL1038609 | 0.79 | TSHR (0.50) | ALOX15ALDH1A1TSHRLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |