Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | METAP2 | P50579 | 8/20 | 0.40 |
| ▸ | METAP1 | P53582 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CAD | P27708 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415889 | 1.00 | ALOX15 (0.44) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL1415713 | 1.00 | ALOX15 (0.44) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL1415988 | 1.00 | ALOX15 (0.44) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL1415500 | 1.00 | ALOX15 (0.44) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL7945977 | 0.86 | ALOX15 (0.41) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL9745060 | 0.83 | CYP2D6 (0.42) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| Hydrochloric Acid SCHEMBL8848952 | 0.82 | ALOX15 (0.50) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL14763884 | 0.82 | ALDH1A1 (0.53) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL18213891 | 0.82 | ALDH1A1 (0.53) | ALOX15ALDH1A1METAP2METAP1LMNA | |
| SCHEMBL112149 | 0.82 | ALDH1A1 (0.53) | ALOX15ALDH1A1METAP2METAP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853224-B2 | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases | INDUSTRIAL RESEARCH LIMITED (NZ) | 2014-10-07 | — | — | US | disclosed |
| US-8383636-B2 | Acyclic amine inhibitors of 5-methytioadenosine phosphorylase and nucleosidase | INDUSTRIAL RESEARCH LIMITED (NZ) | 2013-02-26 | — | — | US | disclosed |
| WO-2008030119-A9 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-09-24 | — | — | WO | disclosed |
| EP-2057165-A1 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008030119-A1 | ACYCLIC AMINE INHIBITORS OF NUCLEOSIDE PHOSPHORYLASES AND HYDROLASES | INDUSTRIAL RESEARCH LIMITED (NZ) | 2008-03-13 | — | — | WO | disclosed |