Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956545 | 0.95 | TSHR (0.55) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL7954415 | 0.94 | ALDH1A1 (0.56) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL7945830 | 0.90 | ALDH1A1 (0.56) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL16178026 | 0.89 | ALDH1A1 (0.65) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL1072287 | 0.86 | TSHR (0.75) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL7954996 | 0.85 | PTGS2 (0.66) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL7636318 | 0.85 | MAPT (0.47) | L3MBTL1ALDH1A1LMNAKMT2AHTT | |
| SCHEMBL1987850 | 0.84 | TSHR (0.76) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL29709169 | 0.84 | TSHR (0.76) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL18668916 | 0.84 | TSHR (0.57) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |