Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GALK1 | P51570 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049899 | 0.82 | GRIN2D (0.49) | PTPN1MCL1RAB9AGRIN2DGRIN2A | |
| SCHEMBL7949396 | 0.78 | MCL1 (0.49) | MCL1HDAC4HDAC2HDAC8CYP1A2 | |
| SCHEMBL5553181 | 0.72 | MEN1 (0.49) | PTPN1NPC1RAB9AMEN1MAPT | |
| SCHEMBL28863139 | 0.70 | NPC1 (0.68) | PTPRCPTPN1BCL2MCL1SMN1; SMN2 | |
| SCHEMBL18545978 | 0.67 | NPC1 (0.66) | PTPRCPTPN1BCL2MCL1SMN1; SMN2 | |
| SCHEMBL12700857 | 0.67 | GSTP1 (0.59) | PTPRCPTPN1BCL2MCL1SMN1; SMN2 | |
| SCHEMBL10936171 | 0.67 | MEN1 (0.60) | PTPRCPTPN1BCL2MCL1SMN1; SMN2 | |
| SCHEMBL22820129 | 0.67 | BCL2 (0.63) | PTPRCPTPN1BCL2MCL1SMN1; SMN2 | |
| SCHEMBL23312093 | 0.66 | NPC1 (0.58) | PTPRCPTPN1BCL2MCL1SMN1; SMN2 | |
| SCHEMBL28914940 | 0.66 | MEN1 (0.63) | PTPRCPTPN1BCL2MCL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252104-B1 | 3,6-DISUBSTITUTED-2-OXYNAPHTHALENE DERIVATIVES; RAW MATERIALS FOR SYNTHESIS OF SUCH MATERIALS AS DYES, PIGMENTS, PHOTOSENSITIVE MATERIALS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0765858-B1 | NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | UENO SEIYAKU OYO KENKYUJO KK (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5847233-A | Naphthol derivatives and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-12-08 | — | — | US | disclosed |
| US-5786523-A | Naphthol derivatives and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0765858-A1 | NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1997-04-02 | — | — | EP | disclosed |