SCHEMBL5553181

SCHEMBL5553181

NC(=O)c1c(O)c(-c2ccccc2)cc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
KDM4E B2RXH2 5/20 0.49
ALDH1A1 P00352 3/20 0.49
HPGD P15428 2/20 0.49
MAPT P10636 2/20 0.49
MPI P34949 1/20 0.49
CYP1A2 P05177 1/20 0.49
GLA P06280 1/20 0.49
CYP2C19 P33261 1/20 0.49
HSD17B10 Q99714 1/20 0.49
GPR84 Q9NQS5 3/20 0.44
BCAT2 O15382 1/20 0.43
PTPN1 P18031 1/20 0.42
RECQL P46063 1/20 0.42
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
RAB9A P51151 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL338938 0.87 MEN1 (0.61) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL7049899 0.86 GRIN2D (0.49) BCAT2PTPN1RAB9AGRM2
SCHEMBL28068266 0.81 GPR84 (0.51) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL7900995 0.80 GRM2 (0.43) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL9624322 0.79 POLB (0.59) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL722165 0.78 BCAT2 (0.47) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL25424740 0.77 MEN1 (0.60) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL27608 0.77 MEN1 (0.56) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL5749296 0.77 ALDH1A1 (0.65) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL8723113 0.76 MEN1 (0.55) MEN1KMT2AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58201692-A None JP disclosed
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
CN-1217940-C Naphthol derivatives UENO SEIYAKU OYO KENKYUJO KK (JP) 2005-09-07 CN disclosed
US-20050112487-A1 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same SHOSHI MASAYUKI (JP) 2005-05-26 US disclosed
US-6849367-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same RICOH COMPANY, LTD. (JP) 2005-02-01 US disclosed
US-20030190540-A1 Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same RICOH COMPANY, LTD. (JP) 2003-10-09 US disclosed
CN-1386120-A Naphthol derivatives UENO SEIYAKU OYO KENKYUJO KK (JP) 2002-12-18 CN disclosed
US-4871633-A PHOTOELECTRICAL CHARGE GENERATING COMPOUND MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-10-03 US disclosed
JP-S58201692-A DIAZO TYPE HEAT SENSITIVE PAPER RICOH CO LTD 1983-11-24 JP disclosed