Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | IKBKB | O14920 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 2/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553181 | 0.86 | MEN1 (0.49) | PTPN1BCAT2RAB9AGRM2 | |
| SCHEMBL7946080 | 0.82 | PTPRC (0.38) | GRIN2DGRIN2AGRIN2BGRIN2CPTPN1 | |
| SCHEMBL5014948 | 0.79 | ESR1 (0.55) | GRIN2DGRIN2AGRIN2BGRIN2CIKBKB | |
| SCHEMBL7949396 | 0.78 | MCL1 (0.49) | ACMSDMCL1 | |
| SCHEMBL16772452 | 0.78 | ESR1 (0.53) | GRIN2DGRIN2AGRIN2BGRIN2CPTPN1 | |
| SCHEMBL27418979 | 0.76 | PLAU (0.49) | — | |
| SCHEMBL27416862 | 0.74 | PLAU (0.47) | RAB9A | |
| SCHEMBL338938 | 0.73 | MEN1 (0.61) | PTPN1DHODH | |
| SCHEMBL6938551 | 0.72 | GRIN2D (0.45) | GRIN2DGRIN2AGRIN2BGRIN2CPTPN1 | |
| SCHEMBL5023242 | 0.71 | PDE4A (0.44) | IKBKBHSD17B1HSD17B2MKNK1F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1163548-C | Toning agent | 株式会社上野制药应用研究所 | 2004-08-25 | — | — | CN | disclosed |
| EP-0882767-B1 | BISAZO COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-6548703-B1 | Toning agent | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2003-04-15 | — | — | US | disclosed |
| US-6252104-B1 | 3,6-DISUBSTITUTED-2-OXYNAPHTHALENE DERIVATIVES; RAW MATERIALS FOR SYNTHESIS OF SUCH MATERIALS AS DYES, PIGMENTS, PHOTOSENSITIVE MATERIALS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2001-06-26 | — | — | US | disclosed |
| CN-1291215-A | Toning agent | UENO SEIYAKU OYO KENKYUJO KK (JP) | 2001-04-11 | — | — | CN | disclosed |
| EP-1043364-A1 | TONING AGENT | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2000-10-11 | — | — | EP | disclosed |
| EP-0765858-B1 | NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | UENO SEIYAKU OYO KENKYUJO KK (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5965715-A | Bisazo compounds and process for the preparation thereof | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0882767-A1 | BISAZO COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5847233-A | Naphthol derivatives and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-12-08 | — | — | US | disclosed |
| US-5786523-A | Naphthol derivatives and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0765858-A1 | NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1997-04-02 | — | — | EP | disclosed |