SCHEMBL7946129

SCHEMBL7946129

O=C(O)c1ccc2c(Br)c(O)c(C(=O)O)cc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.66
GRIN2A Q12879 1/20 0.66
GRIN2B Q13224 1/20 0.66
GRIN2C Q14957 1/20 0.66
PTPN1 P18031 2/20 0.51
AKR1C3 P42330 3/20 0.41
AKR1C2 P52895 3/20 0.41
AKR1C1 Q04828 3/20 0.41
POLB P06746 2/20 0.41
AKR1C4 P17516 2/20 0.41
GPR35 Q9HC97 2/20 0.41
KDM4E B2RXH2 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
PTGS2 P35354 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9623311 0.85 TTR (0.50) GRIN2DGRIN2AGRIN2BGRIN2CPTPN1
SCHEMBL569949 0.85 GRIN2A (0.68) GRIN2DGRIN2AGRIN2BGRIN2CPTPN1
SCHEMBL30382494 0.85 GRIN2A (0.68) GRIN2DGRIN2AGRIN2BGRIN2CPTPN1
SCHEMBL6423930 0.84 PTPN1 (0.56) GRIN2DGRIN2AGRIN2BGRIN2CPTPN1
SCHEMBL9245071 0.83 GRIN2A (0.66) GRIN2DGRIN2AGRIN2BGRIN2CPTPN1
SCHEMBL569344 0.80 GRIN2D (1.00) GRIN2DGRIN2AGRIN2BGRIN2CPTPN1
SCHEMBL6050756 0.79 PTPN1 (0.59) GRIN2DGRIN2AGRIN2BGRIN2CPTPN1
SCHEMBL30943793 0.79 GRIN2D (0.69) GRIN2DGRIN2AGRIN2BGRIN2CAKR1C3
SCHEMBL29558992 0.79 PTPN1 (0.59) GRIN2DGRIN2AGRIN2BGRIN2CPTPN1
SCHEMBL569691 0.79 GRIN2D (0.69) GRIN2DGRIN2AGRIN2BGRIN2CAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1073081-C Naphthol derivatives and process for producing the same UENO SEIYAKU OYO KENKYUJO KK (JP) 2001-10-17 CN disclosed
US-6252104-B1 3,6-DISUBSTITUTED-2-OXYNAPHTHALENE DERIVATIVES; RAW MATERIALS FOR SYNTHESIS OF SUCH MATERIALS AS DYES, PIGMENTS, PHOTOSENSITIVE MATERIALS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2001-06-26 US disclosed
EP-0765858-B1 NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME UENO SEIYAKU OYO KENKYUJO KK (JP) 1999-12-22 EP disclosed
US-5847233-A Naphthol derivatives and process for producing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-12-08 US disclosed
US-5786523-A Naphthol derivatives and process for producing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-07-28 US disclosed
CN-1155882-A Naphthol derivatives and process for producing the same UENO SEIYAKU OYO KENKYUJO KK (JP) 1997-07-30 CN disclosed
EP-0765858-A1 NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1997-04-02 EP disclosed