SCHEMBL9623311

SCHEMBL9623311

O=C(O)c1ccc2c(Br)c(O)c(Br)cc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.50
GRIN2D O15399 2/20 0.48
GRIN2A Q12879 2/20 0.48
GRIN2C Q14957 2/20 0.48
GRIN2B Q13224 1/20 0.48
PTPN1 P18031 1/20 0.45
GPR35 Q9HC97 1/20 0.42
KDM4E B2RXH2 3/20 0.41
MAPT P10636 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
PTGS2 P35354 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7946129 0.85 GRIN2D (0.66) TTRGRIN2DGRIN2AGRIN2CGRIN2B
SCHEMBL11679426 0.83 PTPN1 (0.45) TTRGRIN2DGRIN2AGRIN2CGRIN2B
SCHEMBL9623662 0.77 ESR1 (0.53) GRIN2DGRIN2AGRIN2CPTPN1GPR35
SCHEMBL10080474 0.76 GRIN2D (0.53) TTRGRIN2DGRIN2AGRIN2CPTPN1
SCHEMBL10770350 0.76 ALOX15 (0.41) GRIN2DGRIN2AGRIN2CGRIN2BKDM4E
SCHEMBL29558992 0.74 PTPN1 (0.59) GRIN2DGRIN2AGRIN2CGRIN2BPTPN1
SCHEMBL6050756 0.74 PTPN1 (0.59) GRIN2DGRIN2AGRIN2CGRIN2BPTPN1
SCHEMBL31129058 0.73 BCL2L1 (0.51) PTPN1GPR35KDM4EMAPTCA12
Hydrochloric Acid SCHEMBL9812987 0.72 PTPN1 (0.57) GRIN2DGRIN2AGRIN2CGRIN2BPTPN1
SCHEMBL22289736 0.72 PTPN1 (0.49) GRIN2DGRIN2AGRIN2CPTPN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed