SCHEMBL569949

SCHEMBL569949

O=C(O)c1cc2cc(Br)ccc2c(Br)c1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2A Q12879 2/20 0.68
GRIN2B Q13224 2/20 0.68
GRIN2C Q14957 2/20 0.68
GRIN2D O15399 1/20 0.68
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
RXFP1 Q9HBX9 2/20 0.51
GPR35 Q9HC97 2/20 0.47
GRIN1 Q05586 1/20 0.47
AKR1C3 P42330 3/20 0.46
AKR1C2 P52895 3/20 0.46
AKR1C1 Q04828 3/20 0.46
AKR1C4 P17516 2/20 0.46
KDM4E B2RXH2 1/20 0.44
GLA P06280 1/20 0.44
POLB P06746 1/20 0.41
NPC1 O15118 1/20 0.40
HMGB1 P09429 1/20 0.40
CXCL12 P48061 1/20 0.40
NCEH1 Q6PIU2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382494 1.00 GRIN2A (0.68) GRIN2AGRIN2BGRIN2CGRIN2DMEN1
SCHEMBL9245071 0.98 GRIN2A (0.66) GRIN2AGRIN2BGRIN2CGRIN2DMEN1
SCHEMBL7946129 0.85 GRIN2D (0.66) GRIN2AGRIN2BGRIN2CGRIN2DMEN1
SCHEMBL569239 0.83 GRIN2A (0.49) GRIN2AGRIN2BGRIN2CGRIN2DMEN1
SCHEMBL1223580 0.83 KDM4E (0.50) GRIN2AGRIN2BGRIN2CGRIN2DMEN1
Lithium Ion SCHEMBL9245069 0.83 GRIN2A (0.49) GRIN2AGRIN2BGRIN2CGRIN2DMEN1
SCHEMBL9244803 0.83 GRIN2A (0.49) GRIN2AGRIN2BGRIN2CGRIN2DMEN1
SCHEMBL6351094 0.82 GPR35 (0.65) GRIN2AGRIN2BGRIN2CGRIN2DMEN1
SCHEMBL570624 0.81 KDM4E (0.51) GRIN2AGRIN2BGRIN2CGRIN2DMEN1
SCHEMBL11416204 0.81 ERN1 (0.56) GRIN2AGRIN2BGRIN2CGRIN2DMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9604929-B2 Functionalized carbon nanoparticles and functional polymer fibers prepared using the same KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2017-03-28 US claimed
US-20150204009-A1 FUNCTIONALIZED CARBON NANOPARTICLES AND FUNCTIONAL POLYMER FIBERS PREPARED USING THE SAME KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-07-23 US claimed
US-5451482-A Toner compositions with hydroxy naphthoic acid charge enhancing additives XEROX CORPORATION (US) 1995-09-19 US claimed
EP-4668315-A1 COMPOSITION FOR FORMING PROTECTIVE FILM FOR SEMICONDUCTOR CHIP MANUFACTURE, SEMICONDUCTOR SUBSTRATE, SEMICONDUCTOR CHIP, AND METHOD FOR MANUFACTURING SEMICONDUCTOR CHIP Nissan Chemical Corporation (JP) 2025-12-24 EP disclosed
US-20250361419-A1 COMPOSITION FOR FORMING COATING FILM FOR REMOVING FOREIGN MATTERS AND SEMICONDUCTOR SUBSTRATE NISSAN CHEMICAL CORPORATION (JP) 2025-11-27 US disclosed
EP-4629280-A1 COMPOSITION FOR FORMING COATING FILM FOR FOREIGN SUBSTANCE REMOVAL, AND SEMICONDUCTOR SUBSTRATE Nissan Chemical Corporation (JP) 2025-10-08 EP disclosed
US-12422399-B2 Systems, devices, and methods for gas sensing MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-09-23 US disclosed
US-20240353369-A1 SYSTEMS, DEVICES, AND METHODS FOR GAS SENSING MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-10-24 US disclosed
WO-2024172010-A1 COMPOSITION FOR FORMING PROTECTIVE FILM FOR SEMICONDUCTOR CHIP MANUFACTURE, SEMICONDUCTOR SUBSTRATE, SEMICONDUCTOR CHIP, AND METHOD FOR MANUFACTURING SEMICONDUCTOR CHIP 日産化学株式会社 2024-08-22 WO disclosed
US-12013367-B2 Monolithic 3D integrated circuit for gas sensing and method of making and system using MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-06-18 US disclosed
WO-2024117235-A1 COMPOSITION FOR FORMING COATING FILM FOR FOREIGN SUBSTANCE REMOVAL, AND SEMICONDUCTOR SUBSTRATE 日産化学株式会社 2024-06-06 WO disclosed
WO-2004036311-A2 ANTI-REFLECTIVE COMPOSITIONS COMPRISING TRIAZINE COMPOUNDS BREWER SCIENCE, INC. (US) 2004-04-29 WO disclosed
US-20040072420-A1 Anti-reflective compositions comprising triazine compounds BREWER SCIENCE, INC 2004-04-15 US disclosed
US-20030229120-A1 Novel ligands for the hisb10 zn2+ sites of the r-state insulin hexamer NOVO NORDISK A/S (DK) 2003-12-11 US disclosed
CN-1314906-A Salts of paroxetine SMITHKLINE BEECHAM PLC (GB) 2001-09-26 CN disclosed
US-5451482-A Toner compositions with hydroxy naphthoic acid charge enhancing additives XEROX CORPORATION (US) 1995-09-19 US disclosed
US-5426189-A Dopamine receptor ligands and imaging agents THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1995-06-20 US disclosed
US-5334728-A Dopamine receptor ligands and imaging agents THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1994-08-02 US disclosed
US-5186921-A 3-methoxy-n(1-ethyl-2-pyrrolidinyl)methyl)naphthyl-2-carboxy amide compounds for imaging human brains; good retention stability TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1993-02-16 US disclosed
EP-0393838-A1 Dopamine receptor ligands and imaging agents THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1990-10-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030229120-A1 Novel ligands for the hisb10 zn2+ sites of the r-state insulin hexamer IAPP, IRS1, GPR119 GRIN2A 1751/4885GRIN2B 511/4885GRIN2C 2188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.