Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 9/20 | 0.43 |
| ▸ | HTR3A | P46098 | 4/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954825 | 1.00 | KDM4E (0.46) | KDM4ETYK2HTR3AKDM4CTOP2A | |
| SCHEMBL7960307 | 0.87 | KDM4E (0.55) | KDM4EKDM4CTOP2ATOP2BPIK3CG | |
| SCHEMBL7946345 | 0.84 | KDM4E (0.63) | KDM4ETOP2ATOP2BPIK3CG | |
| SCHEMBL7951788 | 0.84 | KDM4E (0.60) | KDM4EHTR3ATOP2ATOP2BPIK3CG | |
| SCHEMBL7953574 | 0.84 | ELANE (0.52) | TYK2HTR3A | |
| SCHEMBL7957249 | 0.84 | ELANE (0.52) | TYK2HTR3A | |
| SCHEMBL7960474 | 0.84 | CNR1 (0.50) | TYK2 | |
| SCHEMBL7962950 | 0.84 | CNR1 (0.50) | TYK2 | |
| SCHEMBL7953294 | 0.83 | KDM4E (0.65) | KDM4ETOP2ATOP2BPIK3CG | |
| SCHEMBL7963122 | 0.82 | KDM4E (0.51) | KDM4EKDM4CTOP2ATOP2BPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331548-B1 | PREVENTION OR TREATMENT OF CYTOKINE RELATED DISEASES | SUNTORY LIMITED (JP) | 2001-12-18 | — | — | US | disclosed |