Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 9/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960474 | 1.00 | CNR1 (0.50) | CNR1CNR2TYK2ELANEKCNH2 | |
| SCHEMBL7960497 | 0.89 | CNR1 (0.51) | CNR1CNR2ELANEKCNH2KMT2A | |
| SCHEMBL7961804 | 0.87 | CNR1 (0.49) | CNR1CNR2ELANEKCNH2KMT2A | |
| SCHEMBL7961887 | 0.87 | CNR1 (0.49) | CNR1CNR2ELANEKCNH2KMT2A | |
| SCHEMBL7966487 | 0.86 | CNR1 (0.48) | CNR1CNR2ELANEKCNH2KMT2A | |
| SCHEMBL7963003 | 0.85 | PDE4A (0.59) | TYK2KCNH2PDE4APDE4BPDE4C | |
| SCHEMBL7962977 | 0.85 | PDE4A (0.59) | TYK2KCNH2PDE4APDE4BPDE4C | |
| SCHEMBL7962005 | 0.85 | CNR1 (0.48) | CNR1CNR2TYK2ELANEKCNH2 | |
| SCHEMBL7960294 | 0.85 | CNR1 (0.48) | CNR1CNR2TYK2ELANEKCNH2 | |
| SCHEMBL7966465 | 0.85 | CNR1 (0.48) | CNR1CNR2ELANEKCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331548-B1 | PREVENTION OR TREATMENT OF CYTOKINE RELATED DISEASES | SUNTORY LIMITED (JP) | 2001-12-18 | — | — | US | disclosed |
| EP-0978516-A1 | 1-CYCLOALKYL-1,8-NAPHTHYRIDIN-4-ONE DERIVATIVES WITH PHOSPHODIESTERASE IV INHIBITORY ACTIVITY | SUNTORY LIMITED (JP) | 2000-02-09 | — | — | EP | disclosed |