Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233286 | 0.76 | ALDH1A1 (0.33) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL9819871 | 0.76 | TSHR (0.33) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL28891552 | 0.74 | FFAR3 (0.33) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL3061236 | 0.74 | ALDH1A1 (0.32) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL28315588 | 0.74 | CYP1A2 (0.32) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL10907823 | 0.74 | ALDH1A1 (0.32) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL21269713 | 0.74 | ALDH1A1 (0.32) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL11652545 | 0.74 | CHRM1 (0.35) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL21268935 | 0.74 | ALDH1A1 (0.32) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL28315616 | 0.74 | ALDH1A1 (0.32) | ALDH1A1MEN1CYP1A2THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6261814-B1 | MIXING PURIFIED, BIOLOGICALLY-DERIVED REDUCTASE FROM NOCARDIA SPECIES WITH CARBOXYLIC ACID OR DERIVATIVE; PRODUCTION OF VANILLIN FROM VANILLIC ACID | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2001-07-17 | — | — | US | disclosed |
| WO-1998040472-A2 | CARBOXYLIC ACID REDUCTASE, AND METHODS OF USING SAME | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-09-17 | — | — | WO | disclosed |
| US-5795759-A | Carboxylic acid reductase, and methods of using same | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-08-18 | — | — | US | disclosed |