Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28213928 | 0.79 | TSHR (0.42) | TSHRALDH1A1FFAR3USP2MEN1 | |
| SCHEMBL2233286 | 0.78 | ALDH1A1 (0.33) | TSHRALDH1A1FFAR3MEN1CYP1A2 | |
| SCHEMBL11652545 | 0.76 | CHRM1 (0.35) | TSHRALDH1A1FFAR3MEN1CYP1A2 | |
| SCHEMBL21269713 | 0.76 | ALDH1A1 (0.32) | TSHRALDH1A1FFAR3MEN1CYP1A2 | |
| SCHEMBL28315588 | 0.76 | CYP1A2 (0.32) | TSHRALDH1A1FFAR3MEN1CYP1A2 | |
| SCHEMBL7946389 | 0.76 | ALDH1A1 (0.32) | TSHRALDH1A1FFAR3MEN1CYP1A2 | |
| SCHEMBL3061236 | 0.76 | ALDH1A1 (0.32) | TSHRALDH1A1FFAR3USP2MEN1 | |
| SCHEMBL21268935 | 0.76 | ALDH1A1 (0.32) | TSHRALDH1A1FFAR3MEN1CYP1A2 | |
| SCHEMBL10907823 | 0.76 | ALDH1A1 (0.32) | TSHRALDH1A1FFAR3MEN1CYP1A2 | |
| SCHEMBL28330405 | 0.76 | ODC1 (0.34) | TSHRALDH1A1FFAR3MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268460-B1 | NEW PERCUTANEOUS ABSORPTION ENHANCERS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE | Macrochem Corporation (US) | 1991-11-06 | — | — | EP | disclosed |
| US-4861764-A | Percutaneous absorption enhancers, compositions containing same and method of use | MACRO CHEM. CORP. (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0268460-A1 | New percutaneous absorption enhancers, compositions containing same and method of use | Macrochem Corporation (US) | 1988-05-25 | — | — | EP | disclosed |