Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2384962 | 0.85 | P2RX3 (0.46) | P2RX3P2RX2ALOX5APFEN1DYRK1A | |
| SCHEMBL7947388 | 0.84 | P2RX3 (0.43) | P2RX3P2RX2ALOX5APFEN1ATM | |
| SCHEMBL2171499 | 0.82 | P2RX3 (0.61) | P2RX3P2RX2 | |
| SCHEMBL7946500 | 0.79 | P2RX3 (0.47) | P2RX3P2RX2 | |
| SCHEMBL7947489 | 0.72 | P2RX3 (0.50) | P2RX3P2RX2CTSA | |
| SCHEMBL7941678 | 0.71 | P2RX3 (0.67) | P2RX3P2RX2 | |
| SCHEMBL1495761 | 0.71 | P2RX3 (0.47) | P2RX3P2RX2CTSA | |
| SCHEMBL409775 | 0.71 | P2RX3 (0.52) | P2RX3P2RX2ALOX5APFEN1 | |
| SCHEMBL13205459 | 0.71 | P2RX3 (0.52) | P2RX3P2RX2ALOX5APFEN1 | |
| SCHEMBL13014871 | 0.70 | P2RX3 (0.54) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033168-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |