SCHEMBL7946508

SCHEMBL7946508

CN(C)C(=O)[C@@H]1C[C@@H](OS(C)(=O)=O)CN1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.37
ANPEP P15144 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21682443 0.84 ATM (0.42) MMP2ANPEP
SCHEMBL1251161 0.84 ATM (0.42) MMP2ANPEP
SCHEMBL6917231 0.84 ATM (0.42) MMP2ANPEP
SCHEMBL1251167 0.84 ATM (0.42) MMP2ANPEP
SCHEMBL1251163 0.84 ATM (0.42) MMP2ANPEP
SCHEMBL3846917 0.82 MMP2 (0.41) MMP2ANPEP
SCHEMBL3476452 0.81 MMP2 (0.53) MMP2ANPEP
SCHEMBL25319030 0.76 MMP2 (0.36) MMP2ANPEP
SCHEMBL15203426 0.76 MMP2 (0.36) MMP2ANPEP
SCHEMBL17842668 0.76 MMP2 (0.36) MMP2ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6331548-B1 PREVENTION OR TREATMENT OF CYTOKINE RELATED DISEASES SUNTORY LIMITED (JP) 2001-12-18 US disclosed
EP-0978516-A1 1-CYCLOALKYL-1,8-NAPHTHYRIDIN-4-ONE DERIVATIVES WITH PHOSPHODIESTERASE IV INHIBITORY ACTIVITY SUNTORY LIMITED (JP) 2000-02-09 EP disclosed