Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PNLIP | P16233 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938891 | 0.90 | RAB9A (0.60) | TDP1POLBKDM4ENPSR1RAB9A | |
| SCHEMBL7938865 | 0.89 | LMNA (0.64) | TDP1POLBKDM4ERAB9ANPC1 | |
| SCHEMBL7939164 | 0.86 | NPC1 (0.59) | TDP1KDM4ERAB9ANPC1MEN1 | |
| SCHEMBL7947380 | 0.85 | NPC1 (0.53) | TDP1POLBKDM4ENPSR1RAB9A | |
| SCHEMBL6295998 | 0.83 | TDP1 (0.78) | TDP1POLBKDM4ENPSR1RAB9A | |
| SCHEMBL7939069 | 0.79 | LMNA (0.50) | TDP1KDM4ERAB9ANPC1MEN1 | |
| SCHEMBL6819334 | 0.78 | TDP1 (0.58) | TDP1POLBKDM4ENPSR1RAB9A | |
| SCHEMBL6815915 | 0.76 | LMNA (0.46) | TDP1KDM4ERAB9ANPC1MEN1 | |
| SCHEMBL6812039 | 0.76 | LMNA (0.46) | TDP1KDM4ERAB9ANPC1MEN1 | |
| SCHEMBL18503022 | 0.76 | MEN1 (0.75) | TDP1KDM4ERAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |