Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662570 | 0.84 | TP53 (0.53) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7687308 | 0.83 | SMN1; SMN2 (0.58) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7687310 | 0.82 | SMN1; SMN2 (0.60) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6815156 | 0.82 | ALDH1A1 (0.66) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7939055 | 0.80 | MAPT (0.70) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6814852 | 0.79 | MAPT (0.80) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6819231 | 0.79 | MAPT (0.63) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7673080 | 0.79 | MAPT (0.63) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6812047 | 0.78 | MAPT (0.67) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6812187 | 0.77 | MAPT (0.60) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |